| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Away | Essendon | 7.11 53 | 4.3 27 | 26 | Docklands Stadium | 27/08/2022 | Match stats |
| R2 | Home | St Kilda | 1.4 10 | 9.9 63 | -53 | Box Hill City Oval | 04/09/2022 | Match stats |
| R3 | Away | Richmond | 7.2 44 | 1.3 9 | 35 | Punt Road | 11/09/2022 | Match stats |
| R4 | Home | Western Bulldogs | 1.1 7 | 6.1 37 | -30 | Box Hill City Oval | 17/09/2022 | Match stats |
| R5 | Away | Sydney | 4.7 31 | 5.5 35 | -4 | Punt Road | 23/09/2022 | Match stats |
| R6 | Home | West Coast | 6.8 44 | 6.5 41 | 3 | Frankston Oval | 30/09/2022 | Match stats |
| R7 | Home | Port Adelaide | 4.5 29 | 1.10 16 | 13 | Frankston Oval | 08/10/2022 | Match stats |
| R8 | Away | GWS Giants | 4.10 34 | 5.3 33 | 1 | Henson Park | 16/10/2022 | Match stats |
| R9 | Home | Brisbane | 1.1 7 | 9.7 61 | -54 | Frankston Oval | 22/10/2022 | Match stats |
| R10 | Away | Fremantle | 7.7 49 | 7.2 44 | 5 | Fremantle Oval | 29/10/2022 | Match stats |